Searchable abstracts of presentations at key conferences in endocrinology

ea0050p280 | Neuroendocrinology and Pituitary | SFEBES2017

Pituitary radiotherapy causes increased, cardio- and cerebrovascular morbidity, and high Age Standardized Mortality Ratio (ASMR): single centre experience

Jones Alistair , O'Kane Emma , Kieffer Nikki , Bremner Emma , Bhake Ragini , Levy Miles , Reddy Narendra

Background: Pituitary radiotherapy (RT) is known to have metabolic, cardiovascular and cerebrovascular complications due to the effects of radiation on normal pituitary tissue and surrounding neurological structures.Objectives: Retrospective evaluation of effects of RT on pituitary dysfunction, type 2 diabetes mellitus, cardio- and cerebrovascular morbidity and mortality in unselected consecutive pituitary adenomas ...

ea0050ep057 | Neoplasia, Cancer and Late Effects | SFEBES2017

Cardiac Paraganglioma associated with SDHB mutation and elevated 3-methoxytyramine levels

O'Kane Emma , Jones Alistair , Barwell Julian , Bhake Ragini , Reddy Narendra , Levy Miles

Case: We report a rare case of a primary cardiac paraganglioma. A 49-year-old male was found to have elevated3-methoxytyramine (3-MT) levels with normal metanephrines, having undergone a screening test following discovery of SDHB gene mutation, after his 10-year-old niece developed a phaeochromocytoma.The patient demonstrated no hypertension and did not bear signs of catecholamine excess, but on direct questioning...

ea0050ep070 | Neuroendocrinology and Pituitary | SFEBES2017

Tolosa hunt syndrome: a rare cause of hypopituitarism

Jones Alistair , O'Kane Emma , Keifer Nikki , Bremner Emma , Bhake Ragini , Levy Miles , Reddy Narendra

Introduction: Tolosa Hunt Syndrome (THS) is a steroid-responsive idiopathic inflammatory condition affecting cavernous sinus and/or orbital apex causing painful ophthalmoplegia. We present a rare case of THS resulting in hypopituitarism.Case: 45-year-old female presented with 10-day history of headache, periorbital pain and diplopia. Past medical history included bipolar disorder and bilateral below knee amputation ...

ea0050p280 | Neuroendocrinology and Pituitary | SFEBES2017

Pituitary radiotherapy causes increased, cardio- and cerebrovascular morbidity, and high Age Standardized Mortality Ratio (ASMR): single centre experience

Jones Alistair , O'Kane Emma , Kieffer Nikki , Bremner Emma , Bhake Ragini , Levy Miles , Reddy Narendra

Background: Pituitary radiotherapy (RT) is known to have metabolic, cardiovascular and cerebrovascular complications due to the effects of radiation on normal pituitary tissue and surrounding neurological structures.Objectives: Retrospective evaluation of effects of RT on pituitary dysfunction, type 2 diabetes mellitus, cardio- and cerebrovascular morbidity and mortality in unselected consecutive pituitary adenomas ...

ea0050ep057 | Neoplasia, Cancer and Late Effects | SFEBES2017

Cardiac Paraganglioma associated with SDHB mutation and elevated 3-methoxytyramine levels

O'Kane Emma , Jones Alistair , Barwell Julian , Bhake Ragini , Reddy Narendra , Levy Miles

Case: We report a rare case of a primary cardiac paraganglioma. A 49-year-old male was found to have elevated3-methoxytyramine (3-MT) levels with normal metanephrines, having undergone a screening test following discovery of SDHB gene mutation, after his 10-year-old niece developed a phaeochromocytoma.The patient demonstrated no hypertension and did not bear signs of catecholamine excess, but on direct questioning...

ea0050ep070 | Neuroendocrinology and Pituitary | SFEBES2017

Tolosa hunt syndrome: a rare cause of hypopituitarism

Jones Alistair , O'Kane Emma , Keifer Nikki , Bremner Emma , Bhake Ragini , Levy Miles , Reddy Narendra

Introduction: Tolosa Hunt Syndrome (THS) is a steroid-responsive idiopathic inflammatory condition affecting cavernous sinus and/or orbital apex causing painful ophthalmoplegia. We present a rare case of THS resulting in hypopituitarism.Case: 45-year-old female presented with 10-day history of headache, periorbital pain and diplopia. Past medical history included bipolar disorder and bilateral below knee amputation ...